Short Course Description
The course will focus on the role of protein post-translation modifications at the level of individual cells and the whole organism, including in normal developmental processes and in disease. We will highlight modifications such as phosphorylation, ubiquitination, glycosylation, methylation, simulation and others, and we will learn how the various modifications affect cell processes and control signal transduction pathways. Emphasis will be placed on understanding the role of the various modifications for disease development with a focus on neurodegenerative diseases, cancer and metabolic diseases. The course will include seminars on selected articles that will be presented by the students. The articles selected for the seminars will include articles describing the main discoveries that serve as a basis for today's research as well as new groundbreaking articles. The seminars will be held starting from the third lesson and in accordance with the topic of the lesson.
Full Syllabus
