Short Course Description
The purpose of the course is to prepare students for working with the zebrafish and utilizing this model properly in their current and future biomedical research.
The course will cover the history of the field, genetic and imaging methodologies, fish husbandry and the guidelines and instructions regarding fish welfare and will gain hands-on experience in handling, crossing, screening, mutagenesis, transgenesis, behavioral assays and microscopy. A major part of the course will include hands-on experimental work and will, at times, require daily attendance.
Students will be exposed to examples for the utilization of the zebrafish as a disease model. This part will be delivered by experts in their field and will cover the use of zebrafish as a model for neurodegenerative diseases, neurodevelopmental disorders, circadian clock and sleep disorders, eating disorders, zebrafish as a model for neuroendocrine systems development and function and endocrine disorders, metabolic diseases, vascular and lymphatic disorders, zebrafish as a model for cancer, and the use of zebrafish in drug discovery. The exact subject will change from one year to another depending on the development of the field and availability of experts.
Full Syllabus