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Syllabus

Course Number 0452-3123-01
Course Name Tools in Bioinformaticas
Academic Unit The George S. Wise Faculty of Life Sciences -
Cell Research
Lecturer Prof. Itay MayroseContact
Lecturer Mr. Yan LenderContact
Contact Email: itaymay@tauex.tau.ac.il
Office Hours By appointmentBuilding: CohenPorter/Britania-Life Sci , Room: 60
Contact Email: yanl@mail.tau.ac.il
Office HoursBy appointment
Mode of Instruction Lecture
Credit Hours 2
Semester 2022/2
Day Sun
Hours 13:00-15:00
Building Sherman - Life Sciences
Room 009
Course is taught in English
Syllabus Not Found

Short Course Description

Topics: The course Introduces some of the main key tools and programs in bioinformatics. It Mainly aim to provide graduate students basic knowledge and practices in computational tools that can be utilized in computational data analysis. The course is given in English. The course covers the following topics:

1. General and genomic databases
2. BLAST and pairwise alignment
3. Multiple sequence alignment
4. Alignment evaluation with GUIDANCE
5. Phylogeny
6. Evolutionary rates
7. Ensembl Genomic browser
8. Next Generation Sequencing
9. Structural databases, visualization & Structural alignments
10. Functions, pathways & enrichments
11. Motifs discovery
12. Basic utilities in data analysis
13. Guest lecture: Planning NGS experiment for bulk RNA-seq and single cell technologies.


Prerequisites: Basic knowledge in biology (molecular biology, evolution, genetics). Taking the course "Introduction to bioinformatics" is an advantage

Grade: 15% home assignments, 80% final project, 5% weekly assignments.
Class works are given every week as part of the interactive recitation. Submission is mandatory and up to 5 points will be given. In addition, 3 home assignments will be given throughout the semester. Submissions of both are mandatory, but only the latter will be considered in the final grade. The final project emulates a full pipeline of data analysis and as such covers all topics taught in the course.



Full syllabus will be available to registered students only
Course Requirements

Students may be required to submit additional assignments
Full requirements as stated in full syllabus

The specific prerequisites of the course,
according to the study program, appears on the program page of the handbook



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